Study: Opioid overdose suicides lower than previously thought; majority of overdoses accidental

A woman protests with other family and friends who have lost loved ones to OxyContin and opioid overdoses at Purdue Pharma LLP headquarters in Stamford, Conn., Aug. 17, 2018 | Associated press photo by Jessica Hill, St. George News

Accidental overdoses cause 90% of all U.S. opioid-related deaths while suicides account for far fewer of these fatalities than previously thought, a new analysis suggests.

Rising use of heroin and illicit, highly potent synthetic opioids including fentanyl has likely contributed to the unintentional death rate, which surged nine-fold between 2000 and 2017, the researchers said. Opioid suicides also went up during that time but their share of all opioid-related deaths shrank.

In 2017, opioid-related deaths totaled about 47,500 and included 43,000 accidental deaths and 1,880 suicides. The cause of about 2,590 deaths could not be determined.

The study was led by U.S. government researchers who analyzed death certificates for people aged 15 and older. They found that suicides accounted for 4% of all opioid-related deaths. By contrast, a 2018 article in the New England Journal of Medicine estimated that at least 20% to 30% of those deaths are suicides

That estimate came from a review of studies and emergency department data, less accurate than death certificates, said Dr. Mark Olfson, a Columbia University psychiatrist and co-author of the new analysis.

Fentanyl-laced fake oxycodone pills collected during an investigation, date and location not specified | File photo courtesy of the U.S. Attorneys Office for Utah via The Associated Press, St. George News

Knowing that most overdoses are accidental “puts the primary focus of care more squarely on the patient’s addiction,” although doctors should still evaluate their mental health, too, Olfson said.

Dr. Marie Oquendo, a University of Pennsylvania psychiatrist and co-author of the 2018 article, called the new analysis an important effort to firm up the numbers.

The study was published Tuesday in the Journal of the American Medical Association.

Suicides and opioid overdoses have sometimes been lumped together as “deaths of despair” that have contributed to recent decline in U.S. life expectancy. But, said Olfson, “The new findings indicate that opioid overdose and suicide are not as strongly tied as we had imagined.”

Guns, not overdoses, are the leading method of suicide in the United States.

Authors of both reports noted that establishing a death as suicide can be difficult and often relies on medical examiners trying to discern intent. Medical examiners’ training and resources vary widely.

Written by LINDSEY TANNER, Associated Press medical writer.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

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